BDBM50177770 CHEMBL3815101

SMILES O=C1c2ccc(cc2-c2[nH]c3cc(ccc3c12)C#N)-c1ccncc1

InChI Key InChIKey=LTBBEOTYYIIJFZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50177770   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50177770(CHEMBL3815101)
Affinity DataIC50: 1.58E+3nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin) transduced in mouse Ba/F3 cells assessed as reduction in cell viability after 3 days by cell titer glo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2017
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50177770(CHEMBL3815101)
Affinity DataIC50: 5.82E+3nMAssay Description:Inhibition of FLT3 D835Y mutant (unknown origin) transduced in mouse Ba/F3 cells assessed as reduction in cell viability after 3 days by cell titer g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2017
Entry Details Article
PubMed