BDBM50177705 CHEMBL3815146

SMILES OC(=O)C1CCN(CC1)C(=O)c1cc(nc2ccccc12)-c1ccc(Cl)s1

InChI Key InChIKey=WLSZZWQBPVXJQI-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50177705   

TargetSegment polarity protein dishevelled homolog DVL-1(Human)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50177705(CHEMBL3815146)
Affinity DataKd:  1.70nMAssay Description:Binding affinity to His-tagged Dvl-1 PDZ domain (247 to 337 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as dissociat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2017
Entry Details Article
PubMed
TargetSegment polarity protein dishevelled homolog DVL-1(Human)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50177705(CHEMBL3815146)
Affinity DataKd:  3.11E+5nMAssay Description:Binding affinity to His-tagged Dvl-1 PDZ domain (247 to 337 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2017
Entry Details Article
PubMed