BDBM50177662 CHEMBL3813842

SMILES CC1(C)OCCn2c1nc1c(nc(nc21)-c1cnc(N)nc1)N1CCOCC1

InChI Key InChIKey=LGWACEZVCMBSKW-UHFFFAOYSA-N

Data  3 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50177662   

LigandPNGBDBM50177662(CHEMBL3813842)
Affinity DataIC50: 2nMAssay Description:Inhibition of P13Kalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
LigandPNGBDBM50177662(CHEMBL3813842)
Affinity DataIC50: 46nMAssay Description:Inhibition of P13Kbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
LigandPNGBDBM50177662(CHEMBL3813842)
Affinity DataIC50: 10nMAssay Description:Inhibition of P13Kgamma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
LigandPNGBDBM50177662(CHEMBL3813842)
Affinity DataIC50: 3nMAssay Description:Inhibition of P13Kdelta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
University of Calabria

Curated by ChEMBL
LigandPNGBDBM50177662(CHEMBL3813842)
Affinity DataIC50: 70nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
LigandPNGBDBM50177662(CHEMBL3813842)
Affinity DataKi:  2nMAssay Description:Inhibition of recombinant PI3Kalpha (unknown origin) using dioctanoylglycerol-PIP2 as substrate incubated for 30 mins in presence of TAMRA-PIP3 by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
University of Calabria

Curated by ChEMBL
LigandPNGBDBM50177662(CHEMBL3813842)
Affinity DataKi:  70nMAssay Description:Inhibition of human recombinant mTOR (1360 to 2549 residues) expressed in insect cells assessed as inhibition of GFP-labeled 4-EBP1 phosphorylation a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2017
Entry Details Article
PubMed
TargetTarget of rapamycin complex subunit LST8(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50177662(CHEMBL3813842)
Affinity DataKi:  70nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed