BDBM50177315 2-[4-(2-Methyl-quinolin-4-ylmethoxy)-phenyl]-1,1-dioxo-1lambda*6*-[1,2]thiazinane-3-carboxylic acid hydroxyamide::2-[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-1,1-dioxo-[1,2]thiazinane-3-carboxylic acid hydroxyamide::CHEMBL203160

SMILES Cc1cc(COc2ccc(cc2)N2C(CCCS2(=O)=O)C(=O)NO)c2ccccc2n1

InChI Key InChIKey=XVLVIDNHSWHJBN-UHFFFAOYSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50177315   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50177315(2-[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-1,1-d...)
Affinity DataIC50: 3.70nMAssay Description:Inhibitory activity against TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50177315(2-[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-1,1-d...)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50177315(2-[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-1,1-d...)
Affinity DataKi: >2.13E+3nMAssay Description:Binding affinity to MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50177315(2-[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-1,1-d...)
Affinity DataKi: >3.33E+3nMAssay Description:Binding affinity to MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50177315(2-[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-1,1-d...)
Affinity DataKi: >4.95E+3nMAssay Description:Binding affinity to MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50177315(2-[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-1,1-d...)
Affinity DataKi: >5.03E+3nMAssay Description:Binding affinity to MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed