BDBM50177145 5-(2-Chloro-4-fluoro-phenylsulfamoyl)-cyclopent-1-enecarboxylic acid ethyl ester::CHEMBL224199::ethyl 5-[N-(2-chloro-4-fluorophenyl)sulfamoyl]cyclopent-1-ene-1-carboxylate

SMILES CCOC(=O)C1=CCCC1S(=O)(=O)Nc1ccc(F)cc1Cl

InChI Key InChIKey=VJKDBRHDGCPRBZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50177145   

TargetToll-like receptor 4(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50177145(ethyl 5-[N-(2-chloro-4-fluorophenyl)sulfamoyl]cycl...)
Affinity DataIC50: 110nMAssay Description:Inhibition of human TLR4-mediated cytokine production in mouse macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed