BDBM50177103 1-(2'-chlorophenyl)penta-1,4-dien-3-one::CHEMBL224976

SMILES Clc1ccccc1\C=C\C(=O)C=C

InChI Key InChIKey=DIYSCNLXRVKMMK-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50177103   

TargetGlutathione reductase, mitochondrial(Human)
Biochemie-Zentrum Der UniversitäT Heidelberg

Curated by ChEMBL
LigandPNGBDBM50177103(1-(2'-chlorophenyl)penta-1,4-dien-3-one | CHEMBL22...)
Affinity DataIC50: 1.90E+5nMAssay Description:Inhibition of human glutathione reductase in presence of 500 uM GSSG substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutathione reductase, mitochondrial(Human)
Biochemie-Zentrum Der UniversitäT Heidelberg

Curated by ChEMBL
LigandPNGBDBM50177103(1-(2'-chlorophenyl)penta-1,4-dien-3-one | CHEMBL22...)
Affinity DataIC50: 1.85E+4nMAssay Description:Inhibition of human glutathione reductase in presence of 50 uM GSSG substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Biochemie-Zentrum Der UniversitäT Heidelberg

Curated by ChEMBL
LigandPNGBDBM50177103(1-(2'-chlorophenyl)penta-1,4-dien-3-one | CHEMBL22...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Trypanosoma cruzi trypanothione reductase after 5 mins pre-incubation with NADPH in presence of 100 uM TS2 substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutathione reductase, mitochondrial(Human)
Biochemie-Zentrum Der UniversitäT Heidelberg

Curated by ChEMBL
LigandPNGBDBM50177103(1-(2'-chlorophenyl)penta-1,4-dien-3-one | CHEMBL22...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human glutathione reductase after 5 mins pre-incubation with NADPH in presence of 500 uM GSSG substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Biochemie-Zentrum Der UniversitäT Heidelberg

Curated by ChEMBL
LigandPNGBDBM50177103(1-(2'-chlorophenyl)penta-1,4-dien-3-one | CHEMBL22...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of Trypanosoma cruzi trypanothione reductase in presence of 100 uM TS2 substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed