BDBM50176535 5-(isopropylamino)-1-(5-(methylsulfonyl)pyridin-2-yl)-3-(trifluoromethyl)-1H-pyrazole-4-carbonitrile::CHEMBL200406

SMILES CC(C)Nc1c(C#N)c(nn1-c1ccc(cn1)S(C)(=O)=O)C(F)(F)F

InChI Key InChIKey=QRFQALWOIUJSKQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50176535   

TargetProstaglandin G/H synthase 1(Dog)
Veterinary Medicine Research and Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176535(5-(isopropylamino)-1-(5-(methylsulfonyl)pyridin-2-...)
Affinity DataIC50: 4.08E+4nMAssay Description:Inhibitory activity against COX1 in canine whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Dog)
Veterinary Medicine Research and Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176535(5-(isopropylamino)-1-(5-(methylsulfonyl)pyridin-2-...)
Affinity DataIC50: 360nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed