BDBM50176531 1-(5-methanesulfonyl-pyridin-2-yl)-5-(4-methyl-benzylamino)-3-trifluoromethyl-1H-pyrazole-4-carbonitrile::CHEMBL380595

SMILES Cc1ccc(CNc2c(C#N)c(nn2-c2ccc(cn2)S(C)(=O)=O)C(F)(F)F)cc1

InChI Key InChIKey=AGZUSBYIOAVFOC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50176531   

TargetProstaglandin G/H synthase 1(Dog)
Veterinary Medicine Research and Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176531(1-(5-methanesulfonyl-pyridin-2-yl)-5-(4-methyl-ben...)
Affinity DataIC50: 2.15E+4nMAssay Description:Inhibitory activity against COX1 in canine whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Dog)
Veterinary Medicine Research and Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176531(1-(5-methanesulfonyl-pyridin-2-yl)-5-(4-methyl-ben...)
Affinity DataIC50: 115nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed