BDBM50176176 2-(4-(5-amino-3-(pyridin-4-yl)isoxazol-4-yl)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL202404

SMILES Nc1onc(c1-c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F)-c1ccncc1

InChI Key InChIKey=INBHFJIACZSINN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50176176   

TargetMalonyl-CoA decarboxylase, mitochondrial(Human)
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50176176(2-(4-(5-amino-3-(pyridin-4-yl)isoxazol-4-yl)phenyl...)
Affinity DataIC50: 190nMAssay Description:Inhibitory activity against recombinant human MCD MBP fusion proteinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed