BDBM50175707 3-((S)-2-(1-cyano-3-(ethoxycarbonyl)indolizin-5-yloxy)-4-methylpentanamido)-3-phenylpropanoic acid::CHEMBL200830

SMILES CCOC(=O)c1cc(C#N)c2cccc(O[C@@H](CC(C)C)C(=O)NC(CC(O)=O)c3ccccc3)n12

InChI Key InChIKey=GBZIUPAPXTXTRI-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50175707   

TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM50175707(3-((S)-2-(1-cyano-3-(ethoxycarbonyl)indolizin-5-yl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against MPTPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM50175707(3-((S)-2-(1-cyano-3-(ethoxycarbonyl)indolizin-5-yl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against MPTPBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM50175707(3-((S)-2-(1-cyano-3-(ethoxycarbonyl)indolizin-5-yl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against Cdc25A phosphataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM50175707(3-((S)-2-(1-cyano-3-(ethoxycarbonyl)indolizin-5-yl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against PTP1bMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 3(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM50175707(3-((S)-2-(1-cyano-3-(ethoxycarbonyl)indolizin-5-yl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against VHR phosphataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed