BDBM50175706 3-(2-(4-((3-benzoyl-1-cyanoindolizin-5-yl)methoxy)phenyl)-4-methylpentanamido)-3-phenylpropanoic acid::CHEMBL200475

SMILES CC(C)CC(C(=O)NC(CC(O)=O)c1ccccc1)c1ccc(OCc2cccc3c(cc(C(=O)c4ccccc4)n23)C#N)cc1

InChI Key InChIKey=SRAFQSKWPYXHJW-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50175706   

TargetM-phase inducer phosphatase 1(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM50175706(3-(2-(4-((3-benzoyl-1-cyanoindolizin-5-yl)methoxy)...)
Affinity DataIC50: 6.92E+4nMAssay Description:Inhibitory activity against Cdc25A phosphataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM50175706(3-(2-(4-((3-benzoyl-1-cyanoindolizin-5-yl)methoxy)...)
Affinity DataIC50: 8.06E+4nMAssay Description:Inhibitory activity against PTP1bMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM50175706(3-(2-(4-((3-benzoyl-1-cyanoindolizin-5-yl)methoxy)...)
Affinity DataIC50: 7.49E+4nMAssay Description:Inhibitory activity against MPTPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM50175706(3-(2-(4-((3-benzoyl-1-cyanoindolizin-5-yl)methoxy)...)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibitory activity against MPTPBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 3(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM50175706(3-(2-(4-((3-benzoyl-1-cyanoindolizin-5-yl)methoxy)...)
Affinity DataIC50: 7.78E+4nMAssay Description:Inhibitory activity against VHR phosphataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed