BDBM50175522 1-{2-[3-((S)-3,4-Dichloro-phenyl)-1-(3,4,5-trimethoxy-benzoyl)-pyrrolidin-3-yl]-ethyl}-4-phenyl-piperidine-4-carboxylic acid amide::CHEMBL372587::MDL 105,212 (R)-enantiomer

SMILES COc1cc(cc(OC)c1OC)C(=O)N1CC[C@](CCN2CCC(CC2)(C(N)=O)c2ccccc2)(C1)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=WZMVQZJKOVPVGZ-UHFFFAOYSA-N

Data  7 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50175522   

TargetSubstance-K receptor(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50175522(CHEMBL372587 | MDL 105,212 (R)-enantiomer | 1-{2-[...)
Affinity DataIC50: 8.40nMAssay Description:Inhibitory concentration against tachykinin receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50175522(CHEMBL372587 | MDL 105,212 (R)-enantiomer | 1-{2-[...)
Affinity DataIC50: 3.10nMAssay Description:Inhibitory concentration against tachykinin receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Guinea pig)
Hoechst Marion Roussel

Curated by PDSP Ki Database
LigandPNGBDBM50175522(CHEMBL372587 | MDL 105,212 (R)-enantiomer | 1-{2-[...)
Affinity DataKi:  2.12nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details
PubMed
TargetSubstance-P receptor(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50175522(CHEMBL372587 | MDL 105,212 (R)-enantiomer | 1-{2-[...)
Affinity DataKi:  3.11nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details
PubMed
TargetSubstance-K receptor(Golden hamster)
Hoechst Marion Roussel

Curated by PDSP Ki Database
LigandPNGBDBM50175522(CHEMBL372587 | MDL 105,212 (R)-enantiomer | 1-{2-[...)
Affinity DataKi:  6.98nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details
PubMed
TargetSubstance-K receptor(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50175522(CHEMBL372587 | MDL 105,212 (R)-enantiomer | 1-{2-[...)
Affinity DataKi:  8.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details
PubMed
TargetSubstance-K receptor(Bovine)
Hoechst Marion Roussel

Curated by PDSP Ki Database
LigandPNGBDBM50175522(CHEMBL372587 | MDL 105,212 (R)-enantiomer | 1-{2-[...)
Affinity DataKi:  8.49nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details
PubMed
TargetNeuromedin-K receptor(Guinea pig)
Hoechst Marion Roussel

Curated by PDSP Ki Database
LigandPNGBDBM50175522(CHEMBL372587 | MDL 105,212 (R)-enantiomer | 1-{2-[...)
Affinity DataKi:  21nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details
PubMed
TargetSubstance-P receptor(Rat)
Hoechst Marion Roussel

Curated by PDSP Ki Database
LigandPNGBDBM50175522(CHEMBL372587 | MDL 105,212 (R)-enantiomer | 1-{2-[...)
Affinity DataKi:  408nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details
PubMed