BDBM50175500 (S)-4-(1-(methylamino)-3-(4-nitrophenoxy)propyl)phenyl dimethylcarbamate::CHEMBL194372::Dimethyl-carbamic acid 4-[(S)-1-methylamino-3-(4-nitro-phenoxy)-propyl]-phenyl ester

SMILES CN[C@@H](CCOc1ccc(cc1)[N+]([O-])=O)c1ccc(OC(=O)N(C)C)cc1

InChI Key InChIKey=BGGBDKDNDXWHQP-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50175500   

TargetAcetylcholinesterase(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50175500((S)-4-(1-(methylamino)-3-(4-nitrophenoxy)propyl)ph...)
Affinity DataIC50: 101nMAssay Description:Inhibitory concentration against acetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50175500((S)-4-(1-(methylamino)-3-(4-nitrophenoxy)propyl)ph...)
Affinity DataIC50: 42nMAssay Description:Inhibitory concentration against serotonin transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50175500((S)-4-(1-(methylamino)-3-(4-nitrophenoxy)propyl)ph...)
Affinity DataIC50: 42nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50175500((S)-4-(1-(methylamino)-3-(4-nitrophenoxy)propyl)ph...)
Affinity DataIC50: 101nMAssay Description:Inhibition of human AchEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50175500((S)-4-(1-(methylamino)-3-(4-nitrophenoxy)propyl)ph...)
Affinity DataIC50: 101nMAssay Description:Inhibition of mouse brain AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50175500((S)-4-(1-(methylamino)-3-(4-nitrophenoxy)propyl)ph...)
Affinity DataIC50: 42nMAssay Description:Inhibition of rat synaptosome SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50175500((S)-4-(1-(methylamino)-3-(4-nitrophenoxy)propyl)ph...)
Affinity DataIC50: 101nMAssay Description:Inhibition of mouse brain acetylcholinesterase by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50175500((S)-4-(1-(methylamino)-3-(4-nitrophenoxy)propyl)ph...)
Affinity DataIC50: 42nMAssay Description:Inhibition of rat synaptosome SERT assessed as reduction in [3H]5-HT uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50175500((S)-4-(1-(methylamino)-3-(4-nitrophenoxy)propyl)ph...)
Affinity DataIC50: 101nMAssay Description:Inhibition of rat AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50175500((S)-4-(1-(methylamino)-3-(4-nitrophenoxy)propyl)ph...)
Affinity DataIC50: 42nMAssay Description:Inhibition of SERT (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed