BDBM50175409 CHEMBL426837::N-(4-bromophenethyl)-N-((4-(4-cyanobenzyl)-4H-1,2,4-triazol-3-yl)methyl)-4-methoxyquinoline-2-carboxamide

SMILES COc1cc(nc2ccccc12)C(=O)N(CCc1ccc(Br)cc1)Cc1nncn1Cc1ccc(cc1)C#N

InChI Key InChIKey=ADZRJKLOXYZNBT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50175409   

TargetDimer of Protein farnesyltransferase subunit beta(Human)
Janssen Research Foundation

Curated by ChEMBL
LigandPNGBDBM50175409(N-(4-bromophenethyl)-N-((4-(4-cyanobenzyl)-4H-1,2,...)
Affinity DataIC50: 96.5nMAssay Description:Inhibitory activity against K-Ras farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed