BDBM50175391 (R)-1-((R)-1-Biphenyl-3-ylmethyl-pyrrolidin-2-yl)-2-(1,1-dimethyl-2-naphthalen-2-yl-ethylamino)-ethanol::CHEMBL425394

SMILES CC(C)(Cc1ccc2ccccc2c1)NC[C@@H](O)[C@H]1CCCN1Cc1cccc(c1)-c1ccccc1

InChI Key InChIKey=HAVCLXMWRUTARG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50175391   

TargetExtracellular calcium-sensing receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175391((R)-1-((R)-1-Biphenyl-3-ylmethyl-pyrrolidin-2-yl)-...)
Affinity DataIC50: 2.47E+3nMAssay Description:Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed