BDBM50175316 6-(4-chlorophenyl)-3-(2-(4-(2-chlorophenyl)piperazin-1-yl)ethyl)-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione::CHEMBL199876

SMILES Clc1ccc(cc1)-c1cc2c([nH]1)[nH]c(=O)n(CCN1CCN(CC1)c1ccccc1Cl)c2=O

InChI Key InChIKey=XRHMVCVKZQLVNP-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50175316   

TargetD(1A) dopamine receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50175316(6-(4-chlorophenyl)-3-(2-(4-(2-chlorophenyl)piperaz...)
Affinity DataKi:  544nMAssay Description:Binding affinity to dopamine D1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50175316(6-(4-chlorophenyl)-3-(2-(4-(2-chlorophenyl)piperaz...)
Affinity DataKi:  1.51E+3nMAssay Description:Binding affinity to 5HT1AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50175316(6-(4-chlorophenyl)-3-(2-(4-(2-chlorophenyl)piperaz...)
Affinity DataKi:  1.51E+3nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5HT1A in CRL:CD(SD)BR-COBS rat brain hippocampus after 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50175316(6-(4-chlorophenyl)-3-(2-(4-(2-chlorophenyl)piperaz...)
Affinity DataKi:  2.37E+3nMAssay Description:Binding affinity to dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed