BDBM50175251 CHEMBL200796::methyl 3-(phenylamino)-1H-thieno[2,3-c]pyrazole-5-carboxylate

SMILES COC(=O)c1cc2c(Nc3ccccc3)[nH]nc2s1

InChI Key InChIKey=WIVJBVXMFDYZEO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50175251   

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50175251(methyl 3-(phenylamino)-1H-thieno[2,3-c]pyrazole-5-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50175251(methyl 3-(phenylamino)-1H-thieno[2,3-c]pyrazole-5-...)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibitory activity against Plk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50175251(methyl 3-(phenylamino)-1H-thieno[2,3-c]pyrazole-5-...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibitory activity against Akt1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 4(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50175251(methyl 3-(phenylamino)-1H-thieno[2,3-c]pyrazole-5-...)
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibitory activity against Pak4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed