BDBM50175250 CHEMBL370199::methyl 2-(5-carbamoyl-3-methyl-1H-thieno[2,3-c]pyrazol-4-ylamino)-2-oxoacetate

SMILES COC(=O)C(=O)Nc1c(sc2n[nH]c(C)c12)C(N)=O

InChI Key InChIKey=LKKGYKDFEPORRK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50175250   

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50175250(methyl 2-(5-carbamoyl-3-methyl-1H-thieno[2,3-c]pyr...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50175250(methyl 2-(5-carbamoyl-3-methyl-1H-thieno[2,3-c]pyr...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against Akt1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50175250(methyl 2-(5-carbamoyl-3-methyl-1H-thieno[2,3-c]pyr...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibitory activity against Plk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 4(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50175250(methyl 2-(5-carbamoyl-3-methyl-1H-thieno[2,3-c]pyr...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against Pak4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed