BDBM50175237 CHEMBL199528::N-butyl-N-methyl-3-phenyl-1H-thieno[2,3-c]pyrazole-5-carboxamide

SMILES CCCCN(C)C(=O)c1cc2c(n[nH]c2s1)-c1ccccc1

InChI Key InChIKey=DCRJMZNHTPDFNQ-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50175237   

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50175237(N-butyl-N-methyl-3-phenyl-1H-thieno[2,3-c]pyrazole...)
Affinity DataIC50: 350nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 4(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50175237(N-butyl-N-methyl-3-phenyl-1H-thieno[2,3-c]pyrazole...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory activity against Pak4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50175237(N-butyl-N-methyl-3-phenyl-1H-thieno[2,3-c]pyrazole...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory activity against Akt1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 8(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50175237(N-butyl-N-methyl-3-phenyl-1H-thieno[2,3-c]pyrazole...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory activity against COTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50175237(N-butyl-N-methyl-3-phenyl-1H-thieno[2,3-c]pyrazole...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory activity against MK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50175237(N-butyl-N-methyl-3-phenyl-1H-thieno[2,3-c]pyrazole...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory activity against Plk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50175237(N-butyl-N-methyl-3-phenyl-1H-thieno[2,3-c]pyrazole...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory activity against CDK2/Cyclin AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50175237(N-butyl-N-methyl-3-phenyl-1H-thieno[2,3-c]pyrazole...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory activity against p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed