BDBM50175232 (4-methylpiperazin-1-yl)(3-phenyl-1H-thieno[2,3-c]pyrazol-5-yl)methanone::CHEMBL371239

SMILES CN1CCN(CC1)C(=O)c1cc2c(n[nH]c2s1)-c1ccccc1

InChI Key InChIKey=UJXSEZDSHGPMOE-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50175232   

TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50175232((4-methylpiperazin-1-yl)(3-phenyl-1H-thieno[2,3-c]...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory activity against CDK2/Cyclin AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 8(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50175232((4-methylpiperazin-1-yl)(3-phenyl-1H-thieno[2,3-c]...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory activity against COTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50175232((4-methylpiperazin-1-yl)(3-phenyl-1H-thieno[2,3-c]...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory activity against p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 4(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50175232((4-methylpiperazin-1-yl)(3-phenyl-1H-thieno[2,3-c]...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory activity against Pak4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50175232((4-methylpiperazin-1-yl)(3-phenyl-1H-thieno[2,3-c]...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50175232((4-methylpiperazin-1-yl)(3-phenyl-1H-thieno[2,3-c]...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory activity against Plk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50175232((4-methylpiperazin-1-yl)(3-phenyl-1H-thieno[2,3-c]...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory activity against MK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50175232((4-methylpiperazin-1-yl)(3-phenyl-1H-thieno[2,3-c]...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory activity against Akt1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed