BDBM50175201 CHEMBL382939::N-(4-(4-amino-1-(1-(tetrahydro-2H-pyran-4-yl)piperidin-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-2-methoxyphenyl)-1-methyl-1H-benzo[d]imidazole-2-carboxamide

SMILES COc1cc(ccc1NC(=O)c1nc2ccccc2n1C)-c1nn(C2CCN(CC2)C2CCOCC2)c2ncnc(N)c12

InChI Key InChIKey=KHBDGONPDISQDA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50175201   

TargetTyrosine-protein kinase Lck(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175201(N-(4-(4-amino-1-(1-(tetrahydro-2H-pyran-4-yl)piper...)
Affinity DataIC50: 318nMAssay Description:Inhibitory activity against lckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175201(N-(4-(4-amino-1-(1-(tetrahydro-2H-pyran-4-yl)piper...)
Affinity DataIC50: 54nMAssay Description:Inhibitory activity against anti-CD3 mAb-induced IL2 production in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fyn(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175201(N-(4-(4-amino-1-(1-(tetrahydro-2H-pyran-4-yl)piper...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory activity against fynMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed