BDBM50175066 CHEMBL3810053

SMILES CNC(=O)CCCCC[C@H](NC(=O)c1cncs1)c1ncc([nH]1)-c1ccc(cc1)-n1cccn1

InChI Key InChIKey=BGNHMEHXGGQEJV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50175066   

TargetHistone deacetylase 1(Human)
Irbm Science Park

Curated by ChEMBL
LigandPNGBDBM50175066(CHEMBL3810053)
Affinity DataIC50: 2.49E+3nMAssay Description:Inhibition of recombinant human His-tagged HDAC1 expressed in insect cells preincubated for 10 mins followed by addition of FLUOR DE LYS as fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2017
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
IRBM Science Park

Curated by ChEMBL
LigandPNGBDBM50175066(CHEMBL3810053)
Affinity DataIC50: 223nMAssay Description:Inhibition of human recombinant his tagged HDAC3 expressed in baculovirus expression system using FLUOR DE LYS-SIRT1 as fluorogenic substrate preincu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Irbm Science Park

Curated by ChEMBL
LigandPNGBDBM50175066(CHEMBL3810053)
Affinity DataIC50: 2.49E+3nMAssay Description:Inhibition of human recombinant his tagged HDAC1 expressed in baculovirus expression system using FLUOR DE LYS-SIRT1 as fluorogenic substrate preincu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed