BDBM50175019 2,3,8-trihydroxy-6-methoxy-1-(3-methylbut-2-enyl)-5-(2-methylbut-3-en-2-yl)-9H-xanthen-9-one::CHEMBL425926::cudraxanthone D

SMILES [#6]-[#8]-c1cc(-[#8])c2c(oc3cc(-[#8])c(-[#8])c(-[#6]\[#6]=[#6](\[#6])-[#6])c3c2=O)c1C([#6])([#6])[#6]=[#6]

InChI Key InChIKey=LZPBLPZWAPXQFF-UHFFFAOYSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50175019   

TargetSterol O-acyltransferase 2(Human)
National Research Laboratory of Lipid Metabolism and Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50175019(cudraxanthone D | 2,3,8-trihydroxy-6-methoxy-1-(3-...)
Affinity DataIC50: 7.52E+4nMAssay Description:Inhibition of human ACAT2 expressed in Hi5 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
National Research Laboratory of Lipid Metabolism and Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50175019(cudraxanthone D | 2,3,8-trihydroxy-6-methoxy-1-(3-...)
Affinity DataIC50: 5.76E+4nMAssay Description:Inhibition of human ACAT1 expressed in Hi5 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSialidase(Clostridium perfringens)
Graduate School of Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50175019(cudraxanthone D | 2,3,8-trihydroxy-6-methoxy-1-(3-...)
Affinity DataIC50: 278nMAssay Description:Inhibition of Clostridium perfringens neuraminidase by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2012
Entry Details Article
PubMed
TargetSialidase(Clostridium perfringens)
Graduate School of Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50175019(cudraxanthone D | 2,3,8-trihydroxy-6-methoxy-1-(3-...)
Affinity DataKi:  143nMAssay Description:Competitive inhibition of Clostridium perfringens neuraminidase by Lineweaver-Burke plot and Dixon plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2012
Entry Details Article
PubMed
TargetSialidase(Clostridium perfringens)
Graduate School of Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50175019(cudraxanthone D | 2,3,8-trihydroxy-6-methoxy-1-(3-...)
Affinity DataKi:  436nMAssay Description:Apparent binding affinity at Clostridium perfringens neuraminidase by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2012
Entry Details Article
PubMed