BDBM50174954 (S)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phenylethyl)-N-methyl-6-(methylsulfonamidomethyl)chroman-2-carboxamide::CHEMBL200442

SMILES CN([C@H](CN1CC[C@H](O)C1)c1ccccc1)C(=O)[C@@H]1CCc2cc(CNS(C)(=O)=O)ccc2O1

InChI Key InChIKey=DRIJKZBDCJQFOM-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50174954   

TargetCytochrome P450 2D6(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50174954((S)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50174954((S)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataKi:  99nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50174954((S)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataKi: >5.00E+3nMAssay Description:Agonistic activity at mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed