BDBM50174895 (1-benzo{1,3}dioxol-5-ylmethyl-piperidin-4-yl)(5-chloro-1Hindazol-3-yl)amine::CHEMBL383359::N-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-4-yl)-5-chloro-1H-indazol-3-amine

SMILES Clc1ccc2[nH]nc(NC3CCN(Cc4ccc5OCOc5c4)CC3)c2c1

InChI Key InChIKey=QJWWTNKROISUSJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50174895   

TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174895((1-benzo{1,3}dioxol-5-ylmethyl-piperidin-4-yl)(5-c...)
Affinity DataIC50: 20nMAssay Description:Binding affinity to human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174895((1-benzo{1,3}dioxol-5-ylmethyl-piperidin-4-yl)(5-c...)
Affinity DataIC50: 260nMAssay Description:Functional antagonism of MCH-mediated calcium release by FLIPR using human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174895((1-benzo{1,3}dioxol-5-ylmethyl-piperidin-4-yl)(5-c...)
Affinity DataIC50: 16nMAssay Description:Displacement of [125I]MCH from MCHr1 expressed in IMR32 (I3.4.2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed