BDBM50174839 1-(4-aminophenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one::4'-Amino-4-hydroxychalcone::CHEMBL383563

SMILES Nc1ccc(cc1)C(=O)\C=C\c1ccc(O)cc1

InChI Key InChIKey=GJKSOGFGWQZGRL-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50174839   

TargetPolyphenol oxidase 2(White button mushroom)
Department of Functional Crop

Curated by ChEMBL
LigandPNGBDBM50174839(4'-Amino-4-hydroxychalcone | 1-(4-aminophenyl)-3-(...)
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of monophenolase activity of mushroom tyrosinase using as L-tyrosine substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAlpha-amylase(Bacillus licheniformis)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50174839(4'-Amino-4-hydroxychalcone | 1-(4-aminophenyl)-3-(...)
Affinity DataIC50: 2.69E+5nMAssay Description:Inhibitory activity against Bacillus licheniformis alpha amylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Department of Functional Crop

Curated by ChEMBL
LigandPNGBDBM50174839(4'-Amino-4-hydroxychalcone | 1-(4-aminophenyl)-3-(...)
Affinity DataKi:  3.90E+3nMAssay Description:Competitive inhibition of monophenolase activity of mushroom tyrosinase using as L-tyrosine substrate by Lineweaver-Burke plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed