BDBM50174736 CHEMBL3808485

SMILES Cc1ccc(OC2CCN(CC2)c2ncnc3ccc(F)cc23)cn1

InChI Key InChIKey=SMYUEWYXIKCMEA-UHFFFAOYSA-N

Data  8 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50174736   

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50174736(CHEMBL3808485)
Affinity DataEC50:  600nMAssay Description:Positive allosteric modulation of human M4 receptor expressed in CHO cells coexpressing Gqi5 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2017
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50174736(CHEMBL3808485)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human M3More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2017
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50174736(CHEMBL3808485)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human M2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2017
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50174736(CHEMBL3808485)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human M5 receptor expressed in CHOK1 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2017
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50174736(CHEMBL3808485)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human M1 receptor expressed in CHOK1 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2017
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50174736(CHEMBL3808485)
Affinity DataEC50:  575nMAssay Description:Positive allosteric modulation of human M4 receptor expressed in CHO cells coexpressing Gqi5 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2017
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50174736(CHEMBL3808485)
Affinity DataEC50:  950nMAssay Description:Positive allosteric modulation of rat M4 receptor expressed in CHO cells coexpressing Gqi5 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2017
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50174736(CHEMBL3808485)
Affinity DataEC50:  225nMAssay Description:Positive allosteric modulation of rat M4 receptor expressed in CHO cells co-expressing Gqi5 assessed as increase in acetylcholine-induced calcium mob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed