BDBM50174589 CHEMBL3808847

SMILES Cc1sc2ncnc(N3CCC(CC3)C(=O)Nc3ccc(cc3)N3CCNC3=O)c2c1C

InChI Key InChIKey=QQIFTXQBHBBOJX-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50174589   

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50174589(CHEMBL3808847)
Affinity DataEC50:  6.20E+3nMAssay Description:Positive allosteric modulation of human M4 receptor expressed in CHO cells coexpressing Gqi5 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2017
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50174589(CHEMBL3808847)
Affinity DataEC50:  6.17E+3nMAssay Description:Positive allosteric modulation of human M4 receptor expressed in CHO cells coexpressing Gqi5 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2017
Entry Details Article
PubMed