BDBM501742 N-Cyclopentyl-3-[5-({7-methyl-5-[2-(4-morpholinyl)ethoxy]-9-oxo-9H-xanthen-3-yl}oxy)-2-pyridinyl]propanamide::US11028064, Example 56

SMILES Cc1cc(OCCN2CCOCC2)c2oc3cc(Oc4ccc(CCC(=O)NC5CCCC5)nc4)ccc3c(=O)c2c1

InChI Key InChIKey=FXZNLJFFZVRJLO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 501742   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Auckland Uniservices

US Patent
LigandPNGBDBM501742(N-Cyclopentyl-3-[5-({7-methyl-5-[2-(4-morpholinyl)...)
Affinity DataIC50: 100nMAssay Description:IC50 values were determined using the Z′-LYTE activity assay, with ATP concentration used at Km app for the specific assay (500 μM ATP for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
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TargetVascular endothelial growth factor receptor 2(Human)
Auckland Uniservices

US Patent
LigandPNGBDBM501742(N-Cyclopentyl-3-[5-({7-methyl-5-[2-(4-morpholinyl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:IC50 values were determined using the Z′-LYTE activity assay, with ATP concentration used at Km app for the specific assay (500 μM ATP for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
Go to US Patent