BDBM50174150 CHEMBL3809986

SMILES [H][C@]12CNC(=O)c3cc([nH]c13)-c1cccc3nc(C)c(N[C@@H](C)\C=C\C2)nc13

InChI Key InChIKey=DDQXBYGNFGPJRL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50174150   

TargetSerine/threonine-protein kinase pim-2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50174150(CHEMBL3809986)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human full-length Pim2 expressed in Escherichia coli assessed as phosphorylation of biotinylated BAD peptide at Ser 112 preincubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50174150(CHEMBL3809986)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human full-length Pim1 expressed in Escherichia coli assessed as phosphorylation of biotinylated BAD peptide at Ser-112 preincubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details Article
PubMed