BDBM50174027 2-(2-(2-(3-(6-(1-(methylsulfonyl)ethyl)quinolin-8-yl)phenyl)-1-(4-(methylsulfonyl)phenyl)vinyl)thiazol-5-yl)propan-2-ol::CHEMBL198722

SMILES CC(c1cc(-c2cccc(\C=C(\c3ncc(s3)C(C)(C)O)c3ccc(cc3)S(C)(=O)=O)c2)c2ncccc2c1)S(C)(=O)=O

InChI Key InChIKey=VSUBBIZTQLTMFR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50174027   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50174027(2-(2-(2-(3-(6-(1-(methylsulfonyl)ethyl)quinolin-8-...)
Affinity DataIC50: 11nMAssay Description:Inhibitory activity against PDE4CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50174027(2-(2-(2-(3-(6-(1-(methylsulfonyl)ethyl)quinolin-8-...)
Affinity DataIC50: 1.10nMAssay Description:Inhibitory activity against PDE4BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50174027(2-(2-(2-(3-(6-(1-(methylsulfonyl)ethyl)quinolin-8-...)
Affinity DataIC50: 1.70nMAssay Description:Inhibitory activity against PDE4AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50174027(2-(2-(2-(3-(6-(1-(methylsulfonyl)ethyl)quinolin-8-...)
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against PDE4DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed