BDBM50174023 (E)-6-isopropyl-8-(3-(2-(3-methyl-1,2,4-oxadiazol-5-yl)-2-(pyridin-2-yl)vinyl)phenyl)quinoline::CHEMBL197494

SMILES CC(C)c1cc(-c2cccc(\C=C(\c3nc(C)no3)c3ccccn3)c2)c2ncccc2c1

InChI Key InChIKey=NRTPACQHCGILGF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50174023   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50174023((E)-6-isopropyl-8-(3-(2-(3-methyl-1,2,4-oxadiazol-...)
Affinity DataIC50: 5.70nMAssay Description:Inhibitory activity against PDE4CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50174023((E)-6-isopropyl-8-(3-(2-(3-methyl-1,2,4-oxadiazol-...)
Affinity DataIC50: 0.300nMAssay Description:Inhibitory activity against PDE4BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50174023((E)-6-isopropyl-8-(3-(2-(3-methyl-1,2,4-oxadiazol-...)
Affinity DataIC50: 0.600nMAssay Description:Inhibitory activity against PDE4DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50174023((E)-6-isopropyl-8-(3-(2-(3-methyl-1,2,4-oxadiazol-...)
Affinity DataIC50: 0.5nMAssay Description:Inhibitory activity against PDE4AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed