BDBM50174014 4-(3-(6-isopropylquinolin-8-yl)phenyl)-2-methyl-3-(pyridin-4-yl)butan-2-ol::CHEMBL198564

SMILES CC(C)c1cc(-c2cccc(CC(c3ccncc3)C(C)(C)O)c2)c2ncccc2c1

InChI Key InChIKey=AGNPWVFAZVESPJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50174014   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50174014(4-(3-(6-isopropylquinolin-8-yl)phenyl)-2-methyl-3-...)
Affinity DataIC50: 4.40nMAssay Description:Inhibitory activity against PDE4DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50174014(4-(3-(6-isopropylquinolin-8-yl)phenyl)-2-methyl-3-...)
Affinity DataIC50: 1.80nMAssay Description:Inhibitory activity against PDE4BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50174014(4-(3-(6-isopropylquinolin-8-yl)phenyl)-2-methyl-3-...)
Affinity DataIC50: 106nMAssay Description:Inhibitory activity against PDE4CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50174014(4-(3-(6-isopropylquinolin-8-yl)phenyl)-2-methyl-3-...)
Affinity DataIC50: 3.40nMAssay Description:Inhibitory activity against PDE4AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed