BDBM50173939 CHEMBL3809237

SMILES CNC(=O)c1ccc2n([C@@H]3CCC[C@@H](C3)NC(=O)c3ccc(Br)s3)c(nc2c1)-c1ccccc1SC

InChI Key InChIKey=JKMDXZLNRAMVOZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50173939   

LigandPNGBDBM50173939(CHEMBL3809237)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of BCATc (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2017
Entry Details Article
PubMed
LigandPNGBDBM50173939(CHEMBL3809237)
Affinity DataIC50: 158nMAssay Description:Inhibition of BCATm in differentiated primary human adipocytes using L-Serine and L-Leucine as substrate after overnight incubation by reverse-phase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2017
Entry Details Article
PubMed
LigandPNGBDBM50173939(CHEMBL3809237)
Affinity DataIC50: 251nMAssay Description:Inhibition of human BCATm (28 to 392 residues) using L-Leucine and alpha-ketogluterate as substrate assessed as L-glutamate production after 10 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2017
Entry Details Article
PubMed