BDBM50173792 2-(2-aminophenyl)-1-hydroxyethane-1,1-diyldiphosphonic acid::CHEMBL414849::[2-(2-amino-phenyl)-1-hydroxy-1-phosphono-ethyl]-phosphonic acid::hydrogen [2-(2-azaniumylphenyl)-1-hydroxy-1-phosphonatoethyl]phosphonate

SMILES Nc1ccccc1CC(O)(P(O)(O)=O)P(O)(O)=O

InChI Key InChIKey=VJXYJONFUZXZJZ-UHFFFAOYSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50173792   

TargetH(+)-exporting diphosphatase(Trypanosoma brucei)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50173792([2-(2-amino-phenyl)-1-hydroxy-1-phosphono-ethyl]-p...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of recombinant Trypanosoma brucei soluble vacuolar pyrophosphatase expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50173792([2-(2-amino-phenyl)-1-hydroxy-1-phosphono-ethyl]-p...)
Affinity DataIC50: 371nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50173792([2-(2-amino-phenyl)-1-hydroxy-1-phosphono-ethyl]-p...)
Affinity DataIC50: 21.6nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50173792([2-(2-amino-phenyl)-1-hydroxy-1-phosphono-ethyl]-p...)
Affinity DataKi:  3.40nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50173792([2-(2-amino-phenyl)-1-hydroxy-1-phosphono-ethyl]-p...)
Affinity DataKi:  64.6nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed