BDBM50173401 1-[2,2,2-Trifluoro-1-(4'-piperazin-1-yl-biphenyl-4-yl)-ethylamino]-cyclohexanecarboxylic acid cyanomethyl-amide::CHEMBL194914

SMILES FC(F)(F)C(NC1(CCCCC1)C(=O)NCC#N)c1ccc(cc1)-c1ccc(cc1)N1CCNCC1

InChI Key InChIKey=BWTADDUGYRQSQU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50173401   

TargetCathepsin K(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50173401(1-[2,2,2-Trifluoro-1-(4'-piperazin-1-yl-biphenyl-4...)
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against cathepsin K using humanized rabbit enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50173401(1-[2,2,2-Trifluoro-1-(4'-piperazin-1-yl-biphenyl-4...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against cathepsin S from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50173401(1-[2,2,2-Trifluoro-1-(4'-piperazin-1-yl-biphenyl-4...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against cathepsin B from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50173401(1-[2,2,2-Trifluoro-1-(4'-piperazin-1-yl-biphenyl-4...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against cathepsin L from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed