BDBM50172728 CHEMBL3809472

SMILES Nc1nccc2cc(NC3c4ccc(CCOC(=O)Nc5cccc(CNC3=O)c5)cc4)ccc12

InChI Key InChIKey=AHEIEXXGHCSZMY-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50172728   

TargetKallikrein-1(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50172728(CHEMBL3809472)
Affinity DataKi:  35nMAssay Description:Inhibition of purified human tissue kallikrein 1 using H-D-Val-Leu-Arg-AFC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2017
Entry Details Article
PubMed
TargetCoagulation factor VII/Tissue factor(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50172728(CHEMBL3809472)
Affinity DataKi:  510nMAssay Description:Inhibition of recombinant human Tissue factor/factor 7a using S2288 as substrate after 30 to 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2017
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50172728(CHEMBL3809472)
Affinity DataKi:  610nMAssay Description:Inhibition of purified human factor 10a using S2765 as substrate after 30 to 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2017
Entry Details Article
PubMed
TargetTrypsin(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50172728(CHEMBL3809472)
Affinity DataKi:  3.50E+3nMAssay Description:Inhibition of purified human trypsin after 30 to 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2017
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50172728(CHEMBL3809472)
Affinity DataKi:  5.70E+3nMAssay Description:Inhibition of purified human factor 11a after 30 to 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2017
Entry Details Article
PubMed
TargetProthrombin(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50172728(CHEMBL3809472)
Affinity DataKi: >1.30E+4nMAssay Description:Inhibition of purified human thrombin after 30 to 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2017
Entry Details Article
PubMed