BDBM50172514 7-Methyl-2-morpholin-4-ylmethyl-4-oxo-4,7-dihydro-thieno[2,3-b]pyridine-5-carboxylic acid 4-chloro-benzylamide::CHEMBL440033

SMILES Cn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2cc(CN3CCOCC3)sc12

InChI Key InChIKey=WRWZKICFIPWGNY-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50172514   

TargetDNA polymerase catalytic subunit(HHV-5)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172514(7-Methyl-2-morpholin-4-ylmethyl-4-oxo-4,7-dihydro-...)
Affinity DataIC50: 1.10E+3nMpH: 7.5Assay Description:Inhibition of human cytomegalovirus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase alpha catalytic subunit(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172514(7-Methyl-2-morpholin-4-ylmethyl-4-oxo-4,7-dihydro-...)
Affinity DataIC50: 4.00E+4nMpH: 7.5Assay Description:Inhibition of human alpha DNA polymerase (95 uL) activity in a solution containg 6.4 mM HEPES (pH 7.5) upon incubation for 12 minutes at 26 degrees C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase catalytic subunit(HHV-1)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172514(7-Methyl-2-morpholin-4-ylmethyl-4-oxo-4,7-dihydro-...)
Affinity DataIC50: 1.20E+3nMpH: 7.5Assay Description:Inhibition of herpes simplex virus type 1 DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase catalytic subunit(HHV-3)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172514(7-Methyl-2-morpholin-4-ylmethyl-4-oxo-4,7-dihydro-...)
Affinity DataIC50: 4.00E+4nMpH: 7.5Assay Description:Inhibition of Varicella-Zoster virus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase catalytic subunit(HHV-3)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172514(7-Methyl-2-morpholin-4-ylmethyl-4-oxo-4,7-dihydro-...)
Affinity DataIC50: 770nMpH: 7.5Assay Description:Inhibition of Varicella-Zoster virus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase delta catalytic subunit(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172514(7-Methyl-2-morpholin-4-ylmethyl-4-oxo-4,7-dihydro-...)
Affinity DataIC50: 4.00E+4nMpH: 7.5Assay Description:Inhibition of human delta DNA polymerase (95 uL) activity in a solution containg 6.4 mM HEPES (pH 7.5) upon incubation for 12 minutes at 26 degrees C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50172514(7-Methyl-2-morpholin-4-ylmethyl-4-oxo-4,7-dihydro-...)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of hERG expressed in CHO cells by automated patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed