BDBM50172476 2-(2-Fluoro-4'-methoxy-biphenyl-4-yl)-propionic acid::CHEMBL196321

SMILES COc1ccc(cc1)-c1ccc(cc1F)C(C)C(O)=O

InChI Key InChIKey=ADNQRQZIGOHTSZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50172476   

TargetCytochrome P450 2C19(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50172476(2-(2-Fluoro-4'-methoxy-biphenyl-4-yl)-propionic ac...)
Affinity DataIC50: 8.70E+4nMAssay Description:Interaction with human cytochrome P450 isoform 2C19 expressed in baculovirus-insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50172476(2-(2-Fluoro-4'-methoxy-biphenyl-4-yl)-propionic ac...)
Affinity DataIC50: 6.70E+4nMAssay Description:Inhibitory concentration against beta-amyloid-42 (Abeta42) secretion was evaluated in human neuroglioma cells (H4-APP695NL)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed