BDBM50172474 2-(4'-Cyclohexyloxy-2-fluoro-biphenyl-4-yl)-propionic acid::CHEMBL380778

SMILES CC(C(O)=O)c1ccc(c(F)c1)-c1ccc(OC2CCCCC2)cc1

InChI Key InChIKey=JSVKMROCBOUOTF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50172474   

TargetAmyloid-beta precursor protein(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50172474(2-(4'-Cyclohexyloxy-2-fluoro-biphenyl-4-yl)-propio...)
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibitory concentration against beta-amyloid-42 (Abeta42) secretion was evaluated in human neuroglioma cells (H4-APP695NL)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed