BDBM50172468 1-(4-Benzo[b]thiophen-3-yl-3-fluoro-phenyl)-cyclopropanecarboxylic acid::CHEMBL196946

SMILES OC(=O)C1(CC1)c1ccc(-c2csc3ccccc23)c(F)c1

InChI Key InChIKey=OHASMRIPZSZDPE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50172468   

TargetCytochrome P450 2C9(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50172468(1-(4-Benzo[b]thiophen-3-yl-3-fluoro-phenyl)-cyclop...)
Affinity DataIC50: 1.90E+4nMAssay Description:Interaction with human cytochrome P450 isoform 2C9 expressed in baculovirus-insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50172468(1-(4-Benzo[b]thiophen-3-yl-3-fluoro-phenyl)-cyclop...)
Affinity DataIC50: 9.63E+4nMAssay Description:Inhibitory concentration against beta-amyloid-42 (Abeta42) secretion was evaluated in human neuroglioma cells (H4-APP695NL)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed