BDBM50172440 2-(2,4-Dichloro-phenoxy)-N-(4-methyl-2-piperazin-1-yl-quinolin-6-yl)-acetamide::CHEMBL196667

SMILES Cc1cc(nc2ccc(NC(=O)COc3ccc(Cl)cc3Cl)cc12)N1CCNCC1

InChI Key InChIKey=GALAIUNXQRYFIW-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50172440   

TargetMelanin-concentrating hormone receptor 1(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50172440(2-(2,4-Dichloro-phenoxy)-N-(4-methyl-2-piperazin-1...)
Affinity DataIC50: 16nMAssay Description:Displacement of 150p M [125I]MCH from human MCH1R expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50172440(2-(2,4-Dichloro-phenoxy)-N-(4-methyl-2-piperazin-1...)
Affinity DataIC50: 74nMAssay Description:Inhibitory concentration against 10 nM MCH-induced IP3 accumulation in CHO-K1 cells expressing human MCH1R after incubation with [3H]myo-inositolMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50172440(2-(2,4-Dichloro-phenoxy)-N-(4-methyl-2-piperazin-1...)
Affinity DataIC50: 3.70nMAssay Description:Displacement of 15 pM [125I]-MCH from human MCH2R expressed in CHO-K1 in whole-cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50172440(2-(2,4-Dichloro-phenoxy)-N-(4-methyl-2-piperazin-1...)
Affinity DataIC50: 5nMAssay Description:Displacement of 15 pM [125I]MCH from human MCH1R expressed in CHO-K1 in whole-cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50172440(2-(2,4-Dichloro-phenoxy)-N-(4-methyl-2-piperazin-1...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory concentration against human 5-hydroxytryptamine 2C receptor expressed in CHO-K1 cells using [3H]mesulergineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed