BDBM50172268 4-(3-(S)-1-Pyrrolidin-2-ylmethyl-indole-1-sulfonyl)-phenylamine::CHEMBL427184

SMILES Nc1ccc(cc1)S(=O)(=O)n1cc(C[C@@H]2CCCN2)c2ccccc12

InChI Key InChIKey=QDSCCNYUEDYRQW-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50172268   

Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50172268(4-(3-(S)-1-Pyrrolidin-2-ylmethyl-indole-1-sulfonyl...)
Affinity DataIC50: 7.60nMAssay Description:Inhibition of cAMP production in HeLa cells expressing human 5-HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50172268(4-(3-(S)-1-Pyrrolidin-2-ylmethyl-indole-1-sulfonyl...)
Affinity DataKi:  7nMAssay Description:Displacement of [3H]LSD from cloned human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed