BDBM50172206 (4S,4aR)-6-Hydroxy-4a-methyl-1-(S)-methyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid (1-adamantan-1-yl-ethyl)-amide::CHEMBL371990

SMILES CC(NC(=O)[C@@]1(C)CCC[C@@]2(C)[C@H]1CCc1ccc(O)cc21)C12CC3CC(CC(C3)C1)C2

InChI Key

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50172206   

TargetOxysterols receptor LXR-beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172206((4S,4aR)-6-Hydroxy-4a-methyl-1-(S)-methyl-1,2,3,4,...)
Affinity DataIC50: 180nMAssay Description:Inhibitory concentration in LXRSPA beta binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172206((4S,4aR)-6-Hydroxy-4a-methyl-1-(S)-methyl-1,2,3,4,...)
Affinity DataIC50: 90nMAssay Description:Inhibitory concentration in LXRSPA alpha binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172206((4S,4aR)-6-Hydroxy-4a-methyl-1-(S)-methyl-1,2,3,4,...)
Affinity DataEC50: >5.00E+4nMAssay Description:Effective concentration in recombinant human LXRbeta ligand binding domain in homogeneous time-resolved fluorescence assay More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172206((4S,4aR)-6-Hydroxy-4a-methyl-1-(S)-methyl-1,2,3,4,...)
Affinity DataEC50:  140nMAssay Description:Effective concentration in transactivation assay using a chimeric LXR construct in HEK293 cells for LXRalpha receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed