BDBM50172189 ((1S,4aS,10aR)-1,4a-Dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthren-1-yl)-(3-phenyl-piperidin-1-yl)-methanone::CHEMBL196340

SMILES C[C@@]1(CCC[C@@]2(C)[C@H]1CCc1ccccc21)C(=O)N1CCCC(C1)c1ccccc1

InChI Key InChIKey=KCTVTEAWWHOHNZ-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50172189   

TargetOxysterols receptor LXR-alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172189(((1S,4aS,10aR)-1,4a-Dimethyl-1,2,3,4,4a,9,10,10a-o...)
Affinity DataIC50: 360nMAssay Description:Inhibitory concentration in LXRSPA alpha binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172189(((1S,4aS,10aR)-1,4a-Dimethyl-1,2,3,4,4a,9,10,10a-o...)
Affinity DataEC50:  100nMAssay Description:Effective concentration in recombinant human LXRbeta ligand binding domain in homogeneous time-resolved fluorescence assay More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172189(((1S,4aS,10aR)-1,4a-Dimethyl-1,2,3,4,4a,9,10,10a-o...)
Affinity DataIC50: 370nMAssay Description:Inhibitory concentration in LXRSPA beta binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172189(((1S,4aS,10aR)-1,4a-Dimethyl-1,2,3,4,4a,9,10,10a-o...)
Affinity DataEC50:  150nMAssay Description:Effective concentration in transactivation assay using a chimeric LXR construct in HEK293 cells for LXRalpha receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed