BDBM50172006 2-tert-Butyl-5-{3-[2-chloro-4-(2,2,2-trifluoro-ethyl)-phenoxy]-propoxy}-2,3-dihydro-benzofuran-2-carboxylic acid::CHEMBL363780

SMILES CC(C)(C)C1(Cc2cc(OCCCOc3ccc(CC(F)(F)F)cc3Cl)ccc2O1)C(O)=O

InChI Key InChIKey=QKQFLHYSVRUCLQ-UHFFFAOYSA-N

Data  2 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50172006   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172006(2-tert-Butyl-5-{3-[2-chloro-4-(2,2,2-trifluoro-eth...)
Affinity DataIC50: 1.50E+4nMAssay Description:In vitro binding affinity for PPAR-gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172006(2-tert-Butyl-5-{3-[2-chloro-4-(2,2,2-trifluoro-eth...)
Affinity DataEC50:  34nMAssay Description:Effective concentration against hamster PPAR-alpha in Gal4 transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172006(2-tert-Butyl-5-{3-[2-chloro-4-(2,2,2-trifluoro-eth...)
Affinity DataEC50: >3.00E+3nMAssay Description:Effective concentration required to produce 50% of maximal reporter activity in cell based transactivation assay using human PPAR-gamma-GAL4 chimeric...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172006(2-tert-Butyl-5-{3-[2-chloro-4-(2,2,2-trifluoro-eth...)
Affinity DataIC50: 5.00E+4nMAssay Description:In vitro binding affinity for PPAR-deltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172006(2-tert-Butyl-5-{3-[2-chloro-4-(2,2,2-trifluoro-eth...)
Affinity DataEC50:  2nMAssay Description:Effective concentration against human PPAR-alpha in Gal4 transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Dog)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172006(2-tert-Butyl-5-{3-[2-chloro-4-(2,2,2-trifluoro-eth...)
Affinity DataEC50:  2nMAssay Description:Effective concentration against canine PPAR-alpha in Gal4 transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed