BDBM50171941 (2R,6S)-1-Methyl-2,6-bis-((E)-styryl)-piperidine::CHEMBL372435::mesotransdiene

SMILES CN1[C@@H](CCC[C@@H]1\C=C\c1ccccc1)\C=C\c1ccccc1

InChI Key InChIKey=BCHCCPODJPHTTL-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50171941   

TargetSodium-dependent dopamine transporter(Human)
University of Kentucky

Curated by PDSP Ki Database
LigandPNGBDBM50171941(CHEMBL372435 | mesotransdiene | (2R,6S)-1-Methyl-2...)
Affinity DataKi:  43nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
University of Kentucky

Curated by PDSP Ki Database
LigandPNGBDBM50171941(CHEMBL372435 | mesotransdiene | (2R,6S)-1-Methyl-2...)
Affinity DataKi:  277nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
University of Kentucky

Curated by PDSP Ki Database
LigandPNGBDBM50171941(CHEMBL372435 | mesotransdiene | (2R,6S)-1-Methyl-2...)
Affinity DataKi:  1.89E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2012
Entry Details Article
PubMed
TargetSynaptic vesicular amine transporter(Rat)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50171941(CHEMBL372435 | mesotransdiene | (2R,6S)-1-Methyl-2...)
Affinity DataKi:  9.88E+3nMAssay Description:Inhibition of 5 nM [3H]DTBZ binding to Vesicular Monoamine Transporter (VAMT2) of rat vesicle membranes More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50171941(CHEMBL372435 | mesotransdiene | (2R,6S)-1-Methyl-2...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of 3 nM [3H]-MLA binding to Nicotinic acetylcholine receptor alpha7 of rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed