BDBM50171831 4-[8-tert-Butyl-2-oxo-3-(4-trifluoromethyl-phenyl)-1,3-diaza-spiro[4.5]dec-1-ylmethyl]-N-(2H-tetrazol-5-yl)-benzamide::CHEMBL197850

SMILES CC(C)(C)C1CCC2(CN(C(=O)N2Cc2ccc(cc2)C(=O)Nc2nnn[nH]2)c2ccc(cc2)C(F)(F)F)CC1

InChI Key InChIKey=ZMRVHKODSZAOOF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50171831   

TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50171831(4-[8-tert-Butyl-2-oxo-3-(4-trifluoromethyl-phenyl)...)
Affinity DataIC50: 113nMAssay Description:Inhibitory concentration against glucagon-induced cAMP accumulation in human glucagon receptor transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50171831(4-[8-tert-Butyl-2-oxo-3-(4-trifluoromethyl-phenyl)...)
Affinity DataIC50: 135nMAssay Description:Inhibitory concentration against glucagon-induced cAMP accumulation in human glucagon receptor transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed