BDBM50171544 1-(4-But-2-ynyloxy-benzenesulfonyl)-4-pentanoyl-piperazine-2-carboxylic acid hydroxyamide::CHEMBL198100

SMILES CCCCC(=O)N1CCN(C(C1)C(=O)NO)S(=O)(=O)c1ccc(OCC#CC)cc1

InChI Key InChIKey=CYIOQNVVHKTYRH-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50171544   

LigandPNGBDBM50171544(1-(4-But-2-ynyloxy-benzenesulfonyl)-4-pentanoyl-pi...)
Affinity DataIC50: 28nMAssay Description:Inhibitory activity against TACE[ADAM metallopeptidase domain 17] in isolated enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171544(1-(4-But-2-ynyloxy-benzenesulfonyl)-4-pentanoyl-pi...)
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibitory activity against matrix metallopeptidase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171544(1-(4-But-2-ynyloxy-benzenesulfonyl)-4-pentanoyl-pi...)
Affinity DataIC50: 83nMAssay Description:Inhibitory activity against matrix metallopeptidase 13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171544(1-(4-But-2-ynyloxy-benzenesulfonyl)-4-pentanoyl-pi...)
Affinity DataIC50: 209nMAssay Description:Inhibitory activity against matrix metallopeptidase 9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50171544(1-(4-But-2-ynyloxy-benzenesulfonyl)-4-pentanoyl-pi...)
Affinity DataIC50: 28nMAssay Description:Inhibitory activity against TACE[ADAM metallopeptidase domain 17] in isolated enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171544(1-(4-But-2-ynyloxy-benzenesulfonyl)-4-pentanoyl-pi...)
Affinity DataIC50: 83nMAssay Description:Inhibitory activity against matrix metallopeptidase 13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171544(1-(4-But-2-ynyloxy-benzenesulfonyl)-4-pentanoyl-pi...)
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibitory activity against matrix metallopeptidase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed