BDBM50171542 4-(4-But-2-ynyloxy-benzenesulfonyl)-piperazine-1,3-dicarboxylic acid 1-diethylamide 3-hydroxyamide::CHEMBL370825

SMILES CCN(CC)C(=O)N1CCN(C(C1)C(=O)NO)S(=O)(=O)c1ccc(OCC#CC)cc1

InChI Key InChIKey=SQODILRODCBOCF-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50171542   

LigandPNGBDBM50171542(4-(4-But-2-ynyloxy-benzenesulfonyl)-piperazine-1,3...)
Affinity DataIC50: 28nMAssay Description:Inhibitory activity against TACE[ADAM metallopeptidase domain 17] in isolated enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171542(4-(4-But-2-ynyloxy-benzenesulfonyl)-piperazine-1,3...)
Affinity DataIC50: 97nMAssay Description:Inhibitory activity against matrix metallopeptidase 13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171542(4-(4-But-2-ynyloxy-benzenesulfonyl)-piperazine-1,3...)
Affinity DataIC50: 221nMAssay Description:Inhibitory activity against matrix metallopeptidase 9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171542(4-(4-But-2-ynyloxy-benzenesulfonyl)-piperazine-1,3...)
Affinity DataIC50: 1.75E+3nMAssay Description:Inhibitory activity against matrix metallopeptidase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171542(4-(4-But-2-ynyloxy-benzenesulfonyl)-piperazine-1,3...)
Affinity DataIC50: 1.75E+3nMAssay Description:Inhibitory activity against matrix metallopeptidase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50171542(4-(4-But-2-ynyloxy-benzenesulfonyl)-piperazine-1,3...)
Affinity DataIC50: 28nMAssay Description:Inhibitory activity against TACE[ADAM metallopeptidase domain 17] in isolated enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171542(4-(4-But-2-ynyloxy-benzenesulfonyl)-piperazine-1,3...)
Affinity DataIC50: 97nMAssay Description:Inhibitory activity against matrix metallopeptidase 13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed